So I think I will revise my research topic even further as I
believe that my research topic is more of a statement that I’m trying to prove
and at this point, I’m not supposed to prove anything, but define a question
and committing myself to finding the answer. By making a statement and setting out to prove
it, I compromise my objectivity.
At any
rate, I have found an interesting book called “Novel
Systems For The Study Of Human Disease: From Basic Research To Application”
while searching through the UB Library database. Although I haven’t had time to examine all
the chapters yet, chapter pages forty-nine through sixty-nine give detailed
descriptions of how lab rats are manipulated on the genetic level to create a
genetically homogenous test subject population.
The book also explains within these pages how working with a genetically
homogenous population allows researchers to isolate specific genes. The reason researchers would want to isolate
genes is to determine if health problems such as cancer or obesity are genetic
or environmental. If these health
problems can be determine to be genetic, researchers can experiment with gene
modification to either introduce new genes that combat the harmful ones, or
eliminate the harmful ones altogether.
A counterpoint to this methodology as pointed out by the article by Ian
Roberts, is that this will not directly produce some kind of gene therapy
for humans since animal test subjects and humans are biologically different on
almost every level, however, it provides us with a scientific model with which
finding some kind of gene modifier that IS compatible with humans DNA.
I particularly like this blog as it relates to mine which is about genetic animal testing. The book that you chose to view based on rats and experimentation in labs was very interesting to me and I might just use it for my research paper. As I said before very similar to my research topic as well as insightful. This article may be beneficial to your research as well.
ReplyDeleteLen A.. "Insights from human/mouse genome comparisons." Mammalian Genome: 429-436. Print.